TREATMENT STRATEGIES FOR MDR TB AT PULMONOLGOY WARD ALLAMA IQBAL MEMORIAL TEACHING HOSPITAL, SIALKOT

Abstract

To search for MDR-TB strategy to determine the & 
regimen design that was implemented for multi-drug resistant 
tuberculosis (MDR-TB) patients at Allama Iqbal Memorial Teaching 
Hospital and to evaluate the frequency of cure rate, treatment 
failure and death rate.
Methodology: Retrospective descriptive and observational study 
was conducted to collect the data of hundred consecutive patients, 
diagnosed and treated with short term regimen (STR) and long term 
regimen (LTR) regimens at AIMTH
Results: Pooled data reported that success rate was 4% in patients 
who received STR, while there were 2% failure rates and 11% 
death (fatality) during treatment who received LTR. There were 44 
males and 56 females between 10 to 85 years of age. Among them 
70% were with no previous medical ailment, 30% presented with 
comorbidities like Diabetes 26%, Hepatic pathologies 2%, Cardiac 
diseases 1% and Psychiatric problems 1%. Average age was 46 
years and weight was 50 kg.
Conclusion: It was concluded that MDR TB is developing in the 
patients without any age and gender discrimination, but inadequate 
regimen, deficient time duration and lack of awareness were main 
contributing factors. The patients who responded to MDR TB 
treatment were depending upon their past medical and drug history, 
drug along with drug susceptibility test.